Wenzhou Medical University shapes future of cell growth factor research

The Fusion Conference, the highest-level academic conference in the global field of fibroblast growth factor (FGF) research, was held in St Julian’s, from May 8 to 10.

Originating from Fusion Conferences, a premier European academic conference brand, the event was on par with the Gordon Research Conferences (GRC) and brought together the world’s leading professors, founders of disciplines, principal investigators from top international researchinstitutions, R&D executives from multinational pharmaceutical companies and leading experts in clinical medicine.

Li Xiaokun, academician of the Chinese Academy of Engineering and president of Wenzhou Medical University (WMU), served as co-chair of the conference. He participated extensively in academic discussions and led efforts to advance multiple international cooperation initiatives.

The WMU team engaged in academic dialogue with experts from around the world on frontier topics such as FGF and metabolic regulation, the development of long-acting fusion proteins, wound repair and disease treatment.

Professors Moosa Mohammadi, Huang Zhifeng and Zhang Jinsan delivered thematic academic presentations on new theories and discoveries concerning growth factors in kidney disease, metabolic diseases and pulmonary diseases, respectively.

Team members, including Xiao Jian, Wang Xiaojie, Cong Weitao, Chen Gaozhi and Wang Zhouguang, shared their latest research findings through conference posters and other formats.  And a number of international scholars held in-depth individual exchanges with the WMU team, leading to multiple cooperation intentions.

IGFA development seminar

More than 20 internationally renowned professors from countries including the US, the UK, Germany, France, Switzerland, Italy and the Czech Republic attended the development seminar of the International Cell Growth Factor Alliance (IGFA), convened by academician Li .

Li noted that FGF research has entered a critical stage in its transition from basic science to clinical translation, making it imperative to establish an open and sustainable international collaboration platform.

Experts held in-depth discussions on issues such as equality and openness, scientific integrity, translational collaboration and sustainable governance, and reached broad consensus.

Looking ahead, the Alliance will be open to FGF researchers worldwide, help break down barriers related to geography, institutions and seniority, and strongly support the participation of young scientists. At the same time, it aims to uphold academic ethics and research standards, accelerate the translation of basic research findings into clinical applications and industrial development, and establish new mechanisms for research collaboration across national borders.

Professor David Ornitz of Washington University said: “The FGF family comprises numerous members with complex functions, while research efforts across countries have long been relatively dispersed. An organised international alliance will greatly advance collaborative innovation among us.”

Participants in the Fusion Conference. Photos: Wenzhour Medical University

International journal

Another important item on the agenda was the launch of the editorial board of Cytokinology, an international English-language academic journal sponsored by WMU. Published by KeAi, the journal focuses on the full spectrum of cytokine science, covering the entire chain from molecular mechanisms and signalling pathways to disease applications and translational medicine. The launch brought together leading experts from more than 20 countries, including authoritative scholars such as David Ornitz, Sabine Werner and Chiara Francavilla.

Professor Sabine Werner of ETH Zurich in Switzerland noted that the journal responds to the trend of multidisciplinary integration and is of great significance to the development of the growth factor field. Mohammad K. Hajihosseini of the University of East Anglia, in the UK, said that by building an open and shared academic platform, the journal will help draw greater attention from the international academic community to advances in this field.

Open research projects

Also during the conference, WMU officially released its open research projects for the ‘Cell Growth Factor Peak Discipline’ to the global community. The initiative supports high-level research teams and outstanding young talents worldwide in conducting joint research on major scientific issues in the field of growth factors, with complementary support for graduate training and international exchange.

The projects will focus on areas such as AI-based development of FGF agonists and antagonists, exploration of novel regulatory factors, investigation of new disease mechanisms and development of new signal transduction technologies, with the aim of advancing collaborative research among domestic and international teams, promoting the translation of research outcomes and fostering joint talent cultivation.

Looking ahead

According to reports, drawing on its strengths in disciplines such as pharmaceutical sciences, WMU has long maintained an internationally leading position in basic FGF research and translational applications. Through more than three decades of dedicated work, Li Xiaokun’s team has enabled China to become the first country in the world to successfully develop growth factors into clinical drugs.

During the visit to Malta, through a series of initiatives including academic presentations and exchanges, alliance development seminars, the launch of the international journal and the release of open research projects, WMU established an integrated international cooperation network in the global FGF research field that brings together mechanisms, platforms and resources.

Looking ahead, the Wenzhou Medical University intends to continue advancing frontier research in biomedicine and make greater contributions to promoting scientific and technological progress in life and health and serving the country’s overarching strategic priorities.

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